Scientists from the Institute of Nano Science and Technology (INST) have developed a starch-based 'hemostat' material, named calcium-modified carboxymethyl-starch, that can stop life-threatening bleeding after a serious injury.
♦ The Hemostat material is a biodegradable microparticles. It concentrates the natural clotting factors in blood by physically absorbing excess fluid.
♦ The microparticles were prepared by modifying some of the chemical hydroxyl groups on starch to carboxymethyl groups and incorporating the beneficial calcium ions. This combination increases the aggregation of red blood cells (RBCs) and platelets and speeds up the activation to generate the fibrin protein network that forms a stable blood clot.
♦ The microparticles form a cohesive and adherent gel within 30 seconds after contact with blood in lab tests.
♦ The material has increased absorption capacity, improved absorption, inexpensive, biocompatible, and biodegradable.
♦ It is a versatile, potentially life-saving, and inexpensive product that will bring a realistic solution for lower-income economies worldwide.